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Year : 2022  |  Volume : 25  |  Issue : 9  |  Page : 1608-1610

Primary extraskeletal Ewing's sarcoma presenting as an axillary mass: A case report and review of the literature

1 Department of Pathology, Taibah University, Universities Road, Al-Madinah Al-Munawwarah, Madinah, Kingdom of Saudi Arabia
2 Department of Pathology, King Fahad Hospital, Al-Madinah Al-Munawwarah, Madinah, Kingdom of Saudi Arabia

Correspondence Address:
Dr. A M Albasri
Department of Pathology, Faculty of Medicine, Taibah University, Almadinah Almonawarah, Madinah
Kingdom of Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/njcp.njcp_196_22

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Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor predominantly observed in adolescents and young adults, and is characterized by aggressive behavior. So far, only two cases of primary axillary soft tissue EES have been reported in the literature. One of them was a 29-year-old female patient who presented with a lump in her left axilla. Upon examination, an irregular, painless mass, measuring 5 cm × 5 cm × 3 cm, was noted in the left axilla. A histopathological examination of the mass revealed small, round, blue cells with scant cytoplasm, round nuclei, numerous mitosis, and necrosis. An immunohistochemistry (IHC) examination was positive for CD99 and negative for ER, PR, Her2neu, CK7, CK5/6, CD56, CD45, CK-pan, CKHMW, P63, desmin, S100, TdT, vimentin, myogenin, synaptophysin, and chromogranin A. The patient was diagnosed with primary axillary soft tissue EES and was started on neoadjuvant chemotherapy. Twelve months later, she is clinically free from the disease.

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