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Year : 2017  |  Volume : 20  |  Issue : 6  |  Page : 777-781

Blastic plasmacytoid dendritic cell leukemia in a black malian

1 Service de Médecine Hôpital du Mali, Bamako, Mali
2 Service de Pathologie, GHI Le RAINCY-MONTFERMEIL, France
3 Institut National de Recherche en Santé Publique, Mali
4 Service de Médicine Hôpital de GAO, Sossokoira Gao, Mali

Correspondence Address:
Y L Diallo
Charge de Recherche en Hematologie, Service de Medecinehopital du Mali, Bamako
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1119-3077.208955

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Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, clinically aggressive hematologic malignancy, that most commonly manifests as cutaneous lesions. A 19-year-old Malian female was admitted to the Unit of Medicine of Hopital du Mali with anemia, fever, weakness, and weight loss. On physical examination she was wasted, pale, febrile (37.4°C), and had inguinal and axillary lymphadenopathies. The complete blood count found pancytopenia with Hemoglobin level of 4.8 g/dL, Leucocytes count of 1900/μL (neutrophil: 300/μL), and platelets count of 56 000/μL. The ultrasonographic examination found hepatomegaly and splenomegaly. The bone marrow biopsy and flow cytometer analysis were in keeping with a diagnosis of BPDCN. The patient, unfortunately, was lost four months later after her hospital admission due to late diagnosis by septicemia. The early diagnosis and availability of specific drugs for acute leukemia could improve the clinical outcome of patients with BPDCN in Mali.

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