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ORIGINAL ARTICLE
Year : 2010  |  Volume : 13  |  Issue : 1  |  Page : 41-46

Prevalence of hepatitis C virus in HIV infected persons in a tertiary hospital in Nigeria


1 Department of Medicine, University of Benin, Benin City, Edo State, Nigeria
2 Department of Community Health, University of Benin, Benin City, Edo State, Nigeria

Correspondence Address:
E U Eze
Department of Medicine, University of Benin, Benin City, Edo State
Nigeria
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Source of Support: None, Conflict of Interest: None


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Objectives: To assess the prevalence of hepatitis C virus (HCV) infection among HIV/AIDS patients in a tertiary hospital in Nigeria. Methods: All infected persons confirmed by Elisa and aged 15 years and above seen at the University of Benin Teaching Hospital were included in the study. The subjects were recruited over a period of one year. All patients with sickle cell anemia and other immuno compromising diseases were excluded from the study. Age and sex matched controls were pooled from patients attending the outpatient clinics of the hospital who were HIV negatives. A medical history and complete physical examination under bright light was carried out on all the subjects. Assays done for each of the patients were HIV screening by Elisa techniques and confirmed by double Elisa and hepatitis C virus screening. Results: A total of 370 subjects were involved in the study of which 204 were cases (HIV positive patients) while 166 were HIV negative controls. Comparing the patients who were widowed with other marital groups, more of the widows were HIV positive than other marital groups. This difference was found to be statistically significant (X 2 =12.807, df = 1: P = 0.000). Nine (4.4%) HIV positive patients were found to be Hepatitis C seropositive while 4 (2.4%) HIV negative controls were hepatitis C seropositive. There was no statistical difference between the prevalence of Hepatitis C virus infection among HIV positive patients and the controls (HIV negative patients) Conclusion: This study has shown that there is no statistical significant difference between the prevalence of hepatitis C virus infection in HIV positive and HIV negative patients. This is in agreement with findings in other developing countries, in the South/South (Niger Delta) of Nigeria and other regions of Nigeria.


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