Medical and Dental Consultantsí Association of Nigeria
Home - About us - Editorial board - Search - Ahead of print - Current issue - Archives - Submit article - Instructions - Subscribe - Advertise - Contacts - Login 
  Users Online: 1891   Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Year : 2007  |  Volume : 10  |  Issue : 2  |  Page : 126-129

Total antioxidant status in type 2 diabetic patients : experience at University College Hospital (UCH) Ibadan, Nigeria

Department of Chemical Pathology, University College Hospital Ibadan, Nigeria

Correspondence Address:
O M Akinosun
Department of Chemical Pathology, University College Hospital Ibadan, Nigeria

Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 17902504

Rights and PermissionsRights and Permissions

Total antioxidant status (TAS) was measured in 20 Type 2 diabetic patients aged 40-60 years (mean 50 years). Patients were on diet and oral hypoglycemic drug therapy, with fasting plasma glucose (FPG) levels > 7.0 mmol/L. Similar measurements were carried out in 20 apparently healthy individuals within the same age range (mean 46 years) and with FPG levels < 6.1 mmol/L. FPG was measured by glucose oxidase method and TAS by a colourimetric method. Comparing the two groups, TAS was significantly reduced in the Type 2 diabetic patients (0.96 +/- 0.37 Vs 1.61 +/- 0.16 mmol/L) (P < 0.05). An inverse correlation between FPG and TAS suggested the existence of a lower antioxidant defense in poorly controlled Type 2 diabetics. Good control of FPG, could possibly help reduce free radical activity and probably minimize the chronic complications in diabetic patients.

[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 1    

Recommend this journal